The Cancer Research Foundation makes ad hoc grants to support ground-breaking research projects in science. The latest of this is the Small Cell Lung Cancer Project, a team science initiative aimed at small cell lung cancer, a recalcitrant disease which shows promise as a proxy for other small cell and recalcitrant cancers.
The Small Cell Lung Cancer Program
Multiple Principle Investigators · University of Chicago
The Cancer Research Foundation is pleased to announce its latest team science grant assembling an all-star lineup of University of Chicago researchers and clinicians, focused on small cell lung cancer, a deadly and recalcitrant disease that shows promised as a proxy for many cancers that have been left behind in recent advances in cancer care and survival.
Identifying Germline Mutations In Young Patients with MDS
PRINCIPAL INVESTIGATORS: Lucy Godley, MD, PhD - University of Chicago · Carolyn Owen, MD - University of Calgary
This study will be the first to examine the frequency of germline mutations in MDS patients 40 years old or younger, generating data on new alleles that are likely to disrupt bone marrow function and normal blood cell development. This work will also define a group of patients in this cohort with no recognizable mutations by MarrowSeq screening, who will serve as subjects for future non-biased sequencing studies (examining the entire exome) to discover new genes implicated in familial hematopoietic malignancies. Other studies using the MarrowSeq panel are also possible, including examining patients with refractory idiopathic thrombocytopenic purpura, a fraction of whom is likely to also have a genetic basis for their disease.
The Interdiscipinary Leukemia Project
Multiple Principal Investigators · University of Chicago
A major new grant to support novel science in cancer research: The Interdisciplinary Leukemia Project, a six-part systems biology-based interdisciplinary attack on therapy-based Acute Myeloid Leukemia, a secondary cancer that strikes 8 to 10% of cancer survivors.
The Cancer Research Foundation Program in GI Cancer Prevention And Control
Principal Investigator: Nathan Ellis · University of Chicago
In 2005, the CRF made a $1.5 Million grant to the University of Chicago Cancer Research Center (UCCRC) to launch the Cancer Research Foundation Program in Gastrointestinal (GI) Cancer to aid in the building of a comprehensive cancer program, leading efforts in population-based research, genetic risk assessment, computational biology, cancer prevention, detection and treatment. This grant has helped build infrastructure for the GI Program; expand the GI Program model into other cancer areas; and obtain comprehensive status from the National Cancer Institute.
The Bernice Goldblatt Pediatric Pharmacogentics Program
Principal Investigators: Dr. Ramamoorthy Nagasubramanian, Dr. John Cunningham · University of Chicago
In 2004 the Cancer Research Foundation awarded $500,000 to establish a Pediatric Pharmacogenetics Program at the University of Chicago. The overall goal of this project is to discover molecular determinants that influence anticancer drug response and toxicity in patients with sarcoma.
"The Cancer Research Foundation has been instrumental in helping the University of Chicago establish one of the premier programs for development of new anticancer drugs in the country. Our pharmacology program has continued to grow and our investigators have achieved increasing prominence in their areas of expertise. I am now excited to lead an internationally renowned group of investigators dedicated to drug discovery and improved therapies for all patients with cancer."Richard L. Schilsky, M.D.
Professor, Department of Medicine Associate Dean for Clinical Research, Division of the Biological Sciences University of Chicago Medical Center
May 07, 2010