Mark Applebaum, MD - 2015 Young Investigator Award
“Utilizing Hypoxia-Response Models to Identify Novel Neuroblastoma Therapy”
Awarded a $75,000 Young Investigator Award
Similar to other cancers, neuroblastoma tumors have decreased access to oxygen compared to normal cells. This causes changes in the tumor cells that lead to aggressive growth and therapy resistance. We hypothesize that an improved understanding of the genes responsible for this response will allow for the development of more effective treatments for patients with neuroblastoma. We aim to verify the role of several genes we believe are important in this process and will identify additional genes by incorporating information across multiple tumor types in order to find new avenues for target treatments for patients.
"Thanks to the hard work, commitment, and compassion of scientists, researchers, and organizations like the Cancer Research Foundation, there is renewed hope for discovering better treatments and eventually a cure for cancer.
I commend all of you for your outstanding contributions to the field of cancer research. For five decades, your commitment to the crusade against cancer has given hope and comfort to people across the nation."
Former President of the United States
May 05, 1997