Mark Applebaum, MD - 2015 Young Investigator Award
“Utilizing Hypoxia-Response Models to Identify Novel Neuroblastoma Therapy”
Awarded a $75,000 Young Investigator Award
Similar to other cancers, neuroblastoma tumors have decreased access to oxygen compared to normal cells. This causes changes in the tumor cells that lead to aggressive growth and therapy resistance. We hypothesize that an improved understanding of the genes responsible for this response will allow for the development of more effective treatments for patients with neuroblastoma. We aim to verify the role of several genes we believe are important in this process and will identify additional genes by incorporating information across multiple tumor types in order to find new avenues for target treatments for patients.
The Cancer Research Foundation has focused attention on cancer and raised money for life-giving research. We...pay tribute to the scientists who have dedicated themselves to finding a cure and to meet the young researchers who are the next generation of fighters against this disease. The message we send today is that those who suffer from cancer are not alone and that together we can work toward a solution."Richard M. Daley
Mayor, City of Chicago
May 20, 1997