Programs recipients

Bryan Dickinson, PhD - 2014 Young Investigator Award

Assistant Professor, Department of Chemistry   ·   University of Chicago

“Proteases reprogrammed through evolution as novel cancer therapies”

Awarded a $75,000 Young Investigator Award.Bryan Dickinson, PhD

This proposal exploits the investigator and institution’s strengths and capabilities in bioengineering to develop innovative approaches to the treatment of cancer. Specifically, the proposal will examine the reprogramming of human proteases, enzymes that destroy other proteins based on their composition, to combat cancer. Investigators will develop and apply a novel evolution system that will allow them to quickly repurpose human proteases to target and degrade specific cancer-causing proteins of interest. They will then explore the utility of human protease-based cancer therapies as a novel method to control the levels of misregulated, cancer-causing proteins, for the development of completely new therapeutic strategies.

 

Watch Dr. Dickinson present his Young Investigator Project

2016 YIA Interim Report

2017 YIA Final Report