Megan McNerney, MD, PhD - 2013 Young Investigator
“In Vivo Characterization of a Tumor Suppressor Associated with High-Risk Myeloid Neoplasms”
Awarded a $75,000 Cancer Research Foundation Young Investigator Award
CUX1 is a transcription factor gene frequently inactivated in myeloid cancers and certain solid tumors. Myeloid cancers with loss of CUX1 are difficult to treat and carry a poor prognosis.
The proposed research will define the phenotypes and pathways in hematopoietic cells that are altered by CUX1 inactivation and may therefore identify new therapeutic targets that ultimately improve the outcome for patients with these diseases.
The Cancer Research Foundation has focused attention on cancer and raised money for life-giving research. We...pay tribute to the scientists who have dedicated themselves to finding a cure and to meet the young researchers who are the next generation of fighters against this disease. The message we send today is that those who suffer from cancer are not alone and that together we can work toward a solution."Richard M. Daley
Mayor, City of Chicago
May 20, 1997