Manish R. Sharma, MD - 2012 Young Investigator Award
“Disease Progression Models for Biomarkers and Patient-Reported Outcomes in Cancer Patients”
Awarded a $75,000 Young Investigator Award.
The general purpose of this research is to use data from completed cancer clinical trials to guide the design of future trials and thereby improve the drug development process. In the first aim, Dr. Sharma will develop a model (a mathematical equation) that describes the progression of prostate cancer over time. In the second aim, he will develop a model that describes the development of nerve damage that is a side effect of chemotherapy treatment in breast cancer. He will demonstrate how these models can be used to predict outcomes for individual patients (within a range of possibilities) and to answer specific questions that will inform the design of future clinical trials in these diseases, ultimately leading to better treatments.
The Cancer Research Foundation has focused attention on cancer and raised money for life-giving research. We...pay tribute to the scientists who have dedicated themselves to finding a cure and to meet the young researchers who are the next generation of fighters against this disease. The message we send today is that those who suffer from cancer are not alone and that together we can work toward a solution."Richard M. Daley
Mayor, City of Chicago
May 20, 1997