Manish R. Sharma, MD - 2012 Young Investigator Award
“Disease Progression Models for Biomarkers and Patient-Reported Outcomes in Cancer Patients”
Awarded a $75,000 Young Investigator Award.
The general purpose of this research is to use data from completed cancer clinical trials to guide the design of future trials and thereby improve the drug development process. In the first aim, Dr. Sharma will develop a model (a mathematical equation) that describes the progression of prostate cancer over time. In the second aim, he will develop a model that describes the development of nerve damage that is a side effect of chemotherapy treatment in breast cancer. He will demonstrate how these models can be used to predict outcomes for individual patients (within a range of possibilities) and to answer specific questions that will inform the design of future clinical trials in these diseases, ultimately leading to better treatments.
"Thanks to the hard work, commitment, and compassion of scientists, researchers, and organizations like the Cancer Research Foundation, there is renewed hope for discovering better treatments and eventually a cure for cancer.
I commend all of you for your outstanding contributions to the field of cancer research. For five decades, your commitment to the crusade against cancer has given hope and comfort to people across the nation."
Former President of the United States
May 05, 1997