Programs recipients

Bernard A. Liu 2003 - 2004 Bernice Goldblatt Fellow

2003 -2004 Bernice Goldblatt Fellow

Bernard A. LiuCancer biology and signal transduction is my area of specialty. I also focus on using systems biology and proteomics to dissect pathways that are deregulated in diseases such as cancer. I am extremely grateful to be a recipient of the Bernice Goldblatt Fellowship and to have the opportunity to meet with Bernice during my time at the University of Chicago. The family and the foundation have been extremely supportive of my research and provided me the initial steps for beginning my career as a scientist in cancer biology. This support will have an everlasting impression on me and will keep me on my path to finding more new and exciting discoveries in the field of cancer research.

During my PhD studies at the University of Chicago, my research was primarily focused on the Systems Level Analysis of a modular protein interaction domain called the Src Homology 2 or SH2 domain. SH2 domains are important in signaling because they primary domain that recognize phosphotyrosine, which is a modification that is deregulated commonly in cancers as a result of mutations in tyrosine kinases such as HER2 and BCR-Abl.

As a postdoctoral fellow at the Samuel Lunenfeld Research Institute, I work in the laboratory of Tony Pawson, PhD, focusing on new pathways in signal transduction that control cell size and cell growth. I am also interested in knowing more about how inflammation and cell polarity play an important role in tumorigenesis.