Qianfei “Jeffrey” Wang, Ph.D. - 2007 Young Investigator Award
Application of Genomic Approaches in Understanding MLL Fusion Protein Mediated Oncogenic Gene Activation
Fusion proteins occur frequently in several different forms of leukemia. My study aims to identify the process that occurs when these proteins promote the expression of certain types of genes that contribute to these diseases. Using a combination of biochemical and genomic approaches, I will dissect the process by which fusion proteins cause these genes to be expressed. Understanding of this gene expression in leukemia cells may facilitate the development of targeted novel therapeutic agents that could be used to help treat these forms of leukemia correcting the aberrant transcriptional process.
"Thanks to the hard work, commitment, and compassion of scientists, researchers, and organizations like the Cancer Research Foundation, there is renewed hope for discovering better treatments and eventually a cure for cancer.
I commend all of you for your outstanding contributions to the field of cancer research. For five decades, your commitment to the crusade against cancer has given hope and comfort to people across the nation."
Former President of the United States
May 05, 1997