Tanmayi Mankame - 2007-2008 Bernice Goldblatt Scholar
2007 - 2008 Bernice Goldblatt Scholar
It has been an honor to be a Goldblatt Fellowship recipient. For an international student like me, this fellowship provided a unique opportunity to study at a prestigious school and pursue graduate studies in cancer biology, a field that I am very passionate about. It would have been nearly impossible for me to pay for my graduate training without this program, and I am eternally grateful to the Goldblatt family for helping me achieve my educational goals. I have had the pleasure to meet many of the Goldblatt family members at several cancer biology events. I deeply admire their commitment and enthusiasm to support students and young investigators in their efforts to develop new strategies to target cancer.
I specialize in cancer biology and cancer research. My PhD thesis has focused on characterizing a novel anti-angiogenic protein, NOL7 that inhibits tumor angiogenesis by regulating multiple pathways. Angiogenesis is essential for tumors to grow and metastasize to distant sites. Effective targeting of angiogenesis requires understanding of the complex alterations that tumor cells undergo in order to stimulate growth of blood vessels that provide the nutrients essential for survival and growth. My thesis research has described a novel for a known tumor suppressor Rb in inhibiting angiogenesis by transcriptionally activating NOL7. This knowledge can be exploited to design more comprehensive anti-angiogenic therapies that concurrently target multiple angiogenic pathways and therefore hold promise of long-term efficacy.
"Thanks to the hard work, commitment, and compassion of scientists, researchers, and organizations like the Cancer Research Foundation, there is renewed hope for discovering better treatments and eventually a cure for cancer.
I commend all of you for your outstanding contributions to the field of cancer research. For five decades, your commitment to the crusade against cancer has given hope and comfort to people across the nation."
Former President of the United States
May 05, 1997