News letters
Jan 12

Dear Friends,

Happy Holidays from the Cancer Research Foundation! As we approach the end of the year, I want to
take an opportunity to check in with you, our valued supporters, and let you know what the CRF has been
doing in the most recent months and what is happening with the projects we are currently supporting.

You may have noticed that we have not sent out a newsletter recently. As part of our ongoing commitment to keep overhead costs low and practice environmental stewardship, we are cutting down on paper mail and offering more cancer research news via our newly overhauled website (www. cancerresearchfdn . org) as well as through email. See the backside of this letter for a peek at somehighlights from the new website and for more information about how to help us keep you updated while cutting down on paper waste. Once you opt to receive our emails, we'll automatically stop sending youpaper mail updates.

Many exciting developments have taken place in 2010. This fall, five early-career scientists were awarded a Cancer Research Foundation Young Investigator Award. They have all proposed exciting work involved in a
number of different cancer related fields, from using radiation to better locate tumors to targeting therapies for cancers that are particularly related to the Human Papilloma Virus. Each scientist and the work he or she intends to undertake is profiled on the CRF website. In addition, last spring John Cunningham  was awarded the 2010 Fletcher Scholars Award . He plans to use the award to pursue a novel idea about how the actual physical architecture of a cell might affect the development of cancer.

Dr. Cunningham is also one of the Principle Investigators on the Interdisciplinary Leukemia Project, which I am pleased to report is moving forward. As you may remember, this project is made up of sixsubprojects, interrelated and dependent on each other and all focused on therapy related Acute Myeloid Leukemia, a fatal cancer that strikes 8 to 10% of all cancer survivors. While all the subprojects are set up and moving forward, some have already provided interesting results: Subproject 1, tasked with identifying the t~AML genome, has already identified 200 genes that may be related to this disease. I am also pleased to report that the project was recently chosen as a recipient of a Hyundai Hope on Wheels grant of $100,000. The Hyundai grant is especially exciting because its program chooses projects based on the recommendation of a large group of unaffiliated researchers and doctors; hence it represents a real vote

of confidence in this project from the scientific community.

Let us know what you think! We're doing our best to give the most promising scientists a chance to
make big discoveries. If you have a survival story, comment, or suggestion, we want to hear from you.
Contact us through the website, call us at 312.630.0055, or send an email to
Finally, as we approach the end of the year,_please consider making a tax-deductible donation to the
Cancer Research Foundation. Vital projects like these often find themselves chronically short on
funding, and without your generosity some of the greatest advances in cancer science might not have
been possible. Send your donation by using the enclosed envelope, giving through our website, or simply
calling us. The CRF also benefits from generous supporters who include us in their estate planning, make
us the beneficiary of a fundraiser, or deduct a portion of each paycheck for cancer research. However you
choose to do your giving this year, we ask that you remember everyone whose life has been affected by
this terrible disease, as well as the talented men and women working tirelessly to stop it.
Thank so much you for your support, and have a wonderful holiday season.

Best Wishes,

Alexandra Nikitas